Method for producing a time-resolved series of 3D magnetic resonance angiograms during the first passage of contrast agent
AssigneeWisconsin Alumni Research Foundation
InventorsCharles A. Mistretta, Frank R. Korosec, Thomas M. Grist, Richard Frayne, Jason A. Polzin
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Abstract
A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Image frames are reconstructed at each sampling of the central k-space region using the temporally nearest samples from the peripheral k-space regions.
Claims23
A method for acquiring NMR data from a subject after iniection of a contrast agent to produce a series of frame images depicting the passage of contrast agent through a region of interest in the subject by repeatedly acquiring samples from a corresponding k-space during a dynamic study of the subject, the steps comprising:
- sampling a central region of k-space at intervals during the dynamic study at a selected temporal rate;
- sampling peripheral regions of k-space at intervals during the dynamic study at a lower temporal rate;
- producing a series of data sets by forming a data set for each central region k-space sampling, which includes said central region k-space samples and samples derived from temporally adjacent samplings of the peripheral k-space regions;
- and
- reconstructing the series of frame images from the series of data sets.
A method for acquiring NMR data from a subject to produce a series of frame images by repeatedly acquiring samples from a selected k-space during a dynamic study of a three-dimensional region of the subject, the steps comprising:
- sampling a central region of the selected k-space at a temporal rate;
- sampling peripheral regions of the selected k-space at a lower temporal rate;
- forming a data set for each set of central region k-space samples, which includes said central region k-space samples and samples derived from the most temporally adjacent samplings of the peripheral k-space regions;
- and
- reconstructing a three-dimensional frame image from each data set, and;
- in which a further three-dimensional image is produced by subtracting one of said three-dimensional frame images from another one of said three-dimensional frame images.
A method for acquiring NMR data from a subject to produce a series of frame images by repeatedly acquiring samples from a selected k-space during a dynamic study of the subject, the steps comprising:
- sampling a central region of the selected k-space at a temporal rate;
- sampling peripheral regions of the selected k-space at a lower temporal rate;
- forming a data set for each set of central region k-space samples, which includes said central region k-space samples and samples derived from the most temporally adjacent samplings of the peripheral k-space regions;
- and
- reconstructing a frame image from each data set;
- and
- in which there are three different peripheral k-space regions and the k-space is repeatedly sampled during the dynamic study by alternately sampling the central k-space region and one of the three different peripheral k-space regions.
Dependencies are inferred from the claim text.