# US 5,710,341 A · Preparation of .alpha.-chloroalkyl aryl ketones

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- Number: US 5,710,341 A
- Document ID: US5710341A
- Status: Granted
- Kind: A
- Application number: 08/620,317
- Filed: 1996-03-22
- Granted: 1998-01-20
- Earliest claimed: 1995-03-31
- Assignees: BASF SE
- Inventors: Wolfgang Siegel; Walter Dobler; Michael John
- Web page: https://patentgrep.com/patent/US5710341A

## CPC

- C07C 45/63: by introduction of halogen; by substitution of halogen atoms by other halogen atoms
- C07C 201/12: by reactions not involving the formation of nitro groups
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS

## Abstract

A process for preparing .alpha.-chloroalkyl aryl ketones of the formula I ##STR1## where n is 1 to 5, R.sub.1 independently of one another are H, alkyl, alkoxy, aryl, aryloxy, acyloxy, acylamino, halogen or nitro, R.sub.2,3 independently of one another are H, alkyl or aryl, by chlorination of alkyl aryl ketones of the formula II ##STR2## with sulfuryl chloride is described, the chlorination being carried out in the presence of an aliphatic alcohol.

## Claims

### Claim 1

A process for preparing .alpha.-chloroalkyl aryl ketones of the formula I ##STR7## where n is 1 to 5,
R.sub.1 independently of one another are H, alkyl, alkoxy, aryl, aryloxy, acyloxy, acylamino, halogen or nitro,
R.sub.2,3 independently of one another are H, alkyl or aryl,
by chlorination of alkyl aryl ketones of the formula II ##STR8## with sulfuryl chloride, which comprises carrying out the chlorination in the presence of an aliphatic alcohol.

### Claim 2 (depends on 1)

The process of claim 1, wherein from 0.1 to 10 mol of alcohol are employed per mole of alkyl aryl ketone II.

### Claim 3 (depends on 1)

The process of claim 1, wherein a C.sub.1 -C.sub.4 -alcohol is employed.

### Claim 4 (depends on 3)

The process of claim 3, wherein the alcohol employed is methanol.