# US 5,708,134 A · Human AlaGlu-IGF-1

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- Number: US 5,708,134 A
- Document ID: US5708134A
- Status: Granted
- Kind: A
- Application number: 08/444,131
- Filed: 1995-05-18
- Granted: 1998-01-13
- Earliest claimed: 1990-08-20
- Assignees: Novo Nordisk A/S
- Inventors: Lars Skriver; Kim Ry Hejn.ae butted.s; Henrik Dalb.o slashed.ge
- Web page: https://patentgrep.com/patent/US5708134A

## CPC

- C07K 14/65: Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)

## Abstract

This invention is directed to isolated human AlaGlu-IGF-1, a novel compound which exerts IGF-1 activity and is a valuable precursor in the preparation of IGF-1 itself.

## Claims

### Claim 1

Human IGF-1 having the amino terminal extension AlaGlu.
