# US 5,707,981 A · Synergistic pharmaceutical compositions

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 5,707,981 A
- Document ID: US5707981A
- Status: Granted
- Kind: A
- Application number: 08/469,371
- Filed: 1995-06-06
- Granted: 1998-01-13
- Earliest claimed: 1994-07-28
- Assignees: Psorial, L.L.C.
- Inventors: Georges Chriki
- Web page: https://patentgrep.com/patent/US5707981A

## CPC

- A61K 31/57: substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

A pharmaceutical composition comprises a synergistic combination of about 0.01-0.15% by wt. triamcinolone acetonide and about 0.04-0.3% by wt. halcinonide as active ingredients, in combination with a pharmaceutically acceptable carrier.

## Claims

### Claim 1

A pharmaceutical composition comprising triamcinolone acetonide and halcinonide in synergistic and effective amounts in combination with a pharmaceutically acceptable carrier.

### Claim 2

A pharmaceutical composition comprising about 0.1% triamcinolone acetonide and about 0.1% halcinonide in combination with a pharmaceutical carrier.

### Claim 3 (depends on 1)

A pharmaceutical composition according to claim 1, wherein said pharmaceutically acceptable carrier is a topical cream.

### Claim 4

A pharmaceutical composition comprising triamcinolone acetonide and halcinonide in synergistic and effective amounts in combination with one or more of petroleum jelly, lanoline, and lanet wax.

### Claim 5 (depends on 4)

A pharmaceutical composition of claim 4, further comprising water.

### Claim 6

A pharmaceutical composition comprising about 0.1% triamcinolone acetonide, about 0.1% halcinonide, about 45 to 50% vaseline, about 6.5 to 7.5% lanoline, about 12 to 15% lanet wax, and a remainder of water, wherein, the percent values are characterized by weight.

### Claim 7 (depends on 1)

A method for treating psoriasis in a patient comprising topically administering a composition of claim 1.

### Claim 8 (depends on 4)

A method for treating psoriasis in a patient comprising topically administering a composition of claim 4.

### Claim 9 (depends on 6)

A method for treating psoriasis in a patient comprising topically administering a composition of claim 6.

### Claim 10 (depends on 1)

A method for treating dermatitis in a patient comprising topically administering a composition of claim 1.

### Claim 11 (depends on 4)

A method for treating dermatitis in a patient comprising topically administering a composition of claim 4.

### Claim 12 (depends on 6)

A method for treating dermatitis in a patient comprising topically administering a composition of claim 6.

### Claim 13 (depends on 1)

A method for treating eczema in a patient comprising topically administering a composition of claim 1.

### Claim 14 (depends on 4)

A method for treating eczema in a patient comprising topically administering a composition of claim 4.

### Claim 15 (depends on 6)

A method for treating eczema in a patient comprising topically administering a composition of claim 6.