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US 5,707,647 AGranted
Adjunctive polymer system for use with medical device
AssigneeAtrix Laboratories, Inc.
InventorsRichard L. Dunn, Gerald L. Yewey, Jeffrey L. Southard, John E. Urheim
Life of this patent
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Abstract
A medical device which is a surgically implantable device coated with an adjunctive polymer system. The adjunctive polymer system forms a solid matrix when introduced into a human or animal body. The adjunctive polymer system can contain a drug or a medicament which is released over time from the solid matrix. The adjunctive polymer system contacts body tissue into which the surgically implantable device is implanted.
Claims11
A method for sealing a wound in an internal tissue or organ, comprising:
- (a) applying an adjunctive polymer system to a fibrous wound dressing to form a coated wound dressing, wherein the adjunctive polymer system comprises
- a mixture of a pharmaceutically acceptable, biodegradable thermoplastic polymer that is insoluble in water or body fluids, and a biocompatible organic solvent which solubilizes the polymer and is miscible to dispersible in water or body fluids, the polymer having such a molecular weight and such a proportion in the solvent that the solvent is capable of dissipating or dispersing from the polymer system into surrounding tissue fluid whereupon the thermoplastic polymer forms a solid matrix;
- (b) applying the coated wound dressing to the wound in the internal tissue or organ;
- and
- (c) allowing the adjunctive polymer system to coagulate to a solid matrix to seal the wound.
2 more elements
A method for sealing a wound in an internal tissue or organ, comprising:
- (a) applying an adjunctive polymer system to the wound, wherein the adjunctive polymer system comprises
- a mixture of a pharmaceutically acceptable, biodegradable thermoplastic polymer that is insoluble in water or body fluids, and a biocompatible organic solvent which solubilizes the polymer and is miscible to dispersible in water or body fluids, the polymer having such a molecular weight and such a proportion in the solvent that the solvent is capable of dissipating or dispersing from the polymer system into surrounding tissue fluid whereupon the thermoplastic polymer forms a solid matrix;
- (b) applying a fibrous wound dressing onto the adjunctive polymer system on the wound;
- and
- (c) allowing the adjunctive polymer system to coagulate to a solid matrix to seal the wound in conjunction with the fibrous wound dressing.
2 more elements
Dependencies are inferred from the claim text.