# US 5,707,635 A · Gel type cosmetic compositions

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- Number: US 5,707,635 A
- Document ID: US5707635A
- Status: Granted
- Kind: A
- Application number: 08/249,093
- Filed: 1994-05-25
- Granted: 1998-01-13
- Earliest claimed: 1991-10-16
- Assignees: Richardson-Vicks Inc.
- Inventors: George Endel Deckner; Brian Scott Lombardo
- Web page: https://patentgrep.com/patent/US5707635A

## CPC

- A61K 8/8158: {Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers}
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 47/32: Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers {, poly(meth)acrylates, or polyvinyl pyrrolidone}
- A61P 1/04: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A61P 1/08: for nausea, cinetosis or vertigo; Antiemetics
- A61P 7/10: Antioedematous agents; Diuretics
- A61P 9/00: Drugs for disorders of the cardiovascular system
- A61P 9/02: Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A61P 9/04: Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A61P 9/06: Antiarrhythmics
- A61P 9/08: Vasodilators for multiple indications
- A61P 11/14: Antitussive agents
- A61P 15/04: for inducing labour or abortion; Uterotonics
- A61P 17/00: Drugs for dermatological disorders
- A61P 17/16: Emollients or protectives, e.g. against radiation
- A61P 21/02: Muscle relaxants, e.g. for tetanus or cramps
- A61P 23/00: Anaesthetics
- A61P 25/02: for peripheral neuropathies
- A61P 25/18: Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A61P 25/20: Hypnotics; Sedatives
- A61P 25/24: Antidepressants
- A61P 25/26: Psychostimulants, e.g. nicotine, cocaine
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 31/04: Antibacterial agents
- A61P 33/00: Antiparasitic agents
- A61P 33/02: Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P 37/00: Drugs for immunological or allergic disorders
- A61Q 19/00: Preparations for care of the skin
- A61Q 19/04: for chemically tanning the skin (topical sun or radiation screening or tanning preparations A61Q17/04)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A skin care composition in the form of a low pH aqueous gel. The compositions provide improved skinfeel and residue characteristics together with excellent moisturizing, emolliency, rub-in and absorption characteristics.

## Claims

### Claim 1

A skin care composition in the form of an aqueous gel comprising (a) from about 0.05% to about 20% of a non-ionic crosslinked polyacrylamide having a molecular weight of from about 1,000,000 to about 30,000,000 and (b) from about 0.1% to about 20% of a compound selected from the group consisting of salicylic acid, sulfur, resorcinol, N-acetyl cysteine, octopirox, retinoids, benzoyl peroxide, erythromycin, tetracycline, azelaic acid, phenoxy ethanol, phenoxy propanol, ethyl acetate, clindamycin, meclocycline, flavinoids, lactic acid, glycolic acid, pyruvic acid, fumic acid, urea, scymnol sulfate, deoxycholate, cholate, and mixtures thereof, wherein said composition has a pH below 3.5.

### Claim 2 (depends on 1)

A skin care composition according to claim 1 wherein the polyacrylamide comprises monomers selected from acrylamide and methacrylamide which are unsubstituted or substituted with a least one alkyl group having from about 1 to about 5 carbon atoms.

### Claim 3 (depends on 2)

A skin care composition according to claim 2 wherein the polyacrylamide comprises monomers selected from the group consisting of acrylamide, methacrylamide, N-methacrylamide, N-methylmethacrylamide, N,N-dimethylmethacrylamide, N-isopropylacrylamide, N-isopropylmethacrylamide and N,N-dimethylacrylamide.

### Claim 4 (depends on 1)

A skin care composition according to claim 1 wherein said composition further comprises a humectant.

### Claim 5 (depends on 4)

A skin care composition according to claim 4 wherein said humectant is selected from the group consisting of polyhydroxy alcohols, glycerin, hexanetriol, propylene glycol, hexylene glycol, polyethylene glycol, 2-pyrrolidone-5-carboxylic acid, D-panthenol, hyaluronic acid, lactamide monoethanolamine, acetamide monoethanolamine and mixtures thereof.

### Claim 6 (depends on 1)

A skin care composition according to claim 1 wherein said composition further comprises an emollient.

### Claim 7 (depends on 6)

A skin care composition according to claim 6 wherein said emollient is a non-volatile silicone oil selected from the group consisting of polyalkylsiloxanes, polyalkylarylsiloxanes, and polyethersiloxane copolymers.

### Claim 8 (depends on 1)

A skin care composition according to claim 1 wherein the compound (b) is selected from the group consisting of salicylic acid, sulfur, resorcinol, octopirox, retinoic acid and its derivatives, benzoyl peroxide, erythromycin, tetracyclin and mixtures thereof.

### Claim 9 (depends on 1)

A skin care composition according to claim 1, wherein the compound (b) comprises salicylic acid.

### Claim 10 (depends on 1)

A skin care composition according to claim 1, wherein the compound (b) comprises benzyl peroxide.

### Claim 11 (depends on 1)

A skin care composition according to claim 1, wherein the compound (b) comprises retinoic acid.

### Claim 12 (depends on 1)

A skin care composition according to claim 1, wherein the compound (b) comprises lactic acid.

### Claim 13 (depends on 1)

A skin care composition according to claim 1, wherein the compound (b) comprises glycolic acid.

### Claim 14 (depends on 1)

A skin care composition according to claim 1, wherein the compound (b) comprises a retinoid.

### Claim 15

A skin care composition in the form of an aqueous gel comprising (a) from about 0.05% to about 20% of a non-ionic crosslinked polyacrylamide having a molecular weight of from about 1,000,000 to about 30,000,000 and (b) from about 0.1% to about 20% of a compound selected from the group consisting of salicylic acid, sulfur, resorcinol, N-acetyl cysteine, octopirox, retinoids, benzoyl peroxide, erythromycin, tetracycline, azelaic acid, phenoxy ethanol, phenoxy propanol, ethyl acetate, clindamycin, meclocycline, flavinoids, lactic acid, glycolic acid, pyruvic acid, fumic acid, urea, scymnol sulfate, deoxycholate, cholate, and mixtures thereof, wherein said composition has a pH below about 3.0.