Apparatus and method to reduce restenosis after arterial intervention
AssigneeThe Trustees of Columbia University in the City of New York
InventorJudah Z. Weinberger
Life of this patent
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Abstract
An apparatus guided by a guidewire within a patient's artery for reducing restenosis after arterial intervention in the patient's artery. A radiation dose delivery wire with a radiation source encapsulated within its distal end is inserted into a blind lumen in a balloon catheter to deliver radiation to a target area of the patient's artery.
Claims9
An apparatus for reducing restenosis after arterial intervention in a patient's artery comprising:
- a balloon catheter with a fluid delivery port connected thereto;
- and
- a radioactive fluid inserted into the balloon catheter through the fluid delivery port, said radioactive fluid being selected from the group consisting of non-iodine and non-phosphorus based radioisotopes that decay with emission of beta plus or beta minus radiation, that have a half-life of between approximately 1 and 72 hours, that have an average decay energy of approximately 500-2000 keV, and that have radiation intensity of greater than or equal to approximately 50%, said radiation intensity being measured in % per decay.
A method for reducing restenosis after arterial intervention in a patient's artery comprising:
- inserting a balloon catheter with a fluid delivery port connected thereto into the patient's artery;
- providing a radioactive fluid selected from the group consisting of non-iodine and nonphosphorus based radioisotopes that decay with emission of beta plus or beta minus radiation, that have a half-life of between approximately 1 and 72 hours, that have an average decay energy of approximately 500-2000 KeV, and that have radiation intensity of greater than or equal to approximately 50%, said radiation intensity being measured in % per decay;
- and
- inserting the radioactive fluid into the balloon catheter through the fluid delivery port.
A method for reducing restenosis after arterial intervention in a patient's artery comprising:
- inserting a balloon catheter with a fluid delivery port connected thereto into the patient's artery;
- and
- selecting a radioactive fluid from the group consisting of non-iodine and nonphosphorus based radioisotopes that decay with emission of beta plus or beta minus radiation, that have a half-life of between approximately 1 and 72 hours, that have an average decay energy of approximately 500-2000 KeV, and that have radiation intensity of greater than or equal to approximately 50%, said radiation intensity being measured in % per decay;
- and
- inserting the radioactive fluid into the balloon catheter through the fluid delivery port.
Dependencies are inferred from the claim text.