# US 5,706,811 A · Method and apparatus for setting reference point for organic measurement > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 5,706,811 A - Document ID: US5706811A - Status: Granted - Kind: A - Application number: 08/564,559 - Filed: 1995-11-29 - Granted: 1998-01-13 - Earliest claimed: 1994-11-30 - Assignees: Director-General of Agency of Industrial Science and Technology - Inventors: Tsunehiro Takeda; Hiroshi Endo; Toru Kumagai - Web page: https://patentgrep.com/patent/US5706811A ## CPC - A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging - A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers} - A61B 5/4547: {Evaluating teeth} - A61B 2090/363: {Use of fiducial points} - A61B 2090/3954: {magnetic, e.g. NMR or MRI} - A61B 2090/3958: {emitting a signal} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract An apparatus includes the position determining members for determining the relative position between the reference frame and the head utilizing at least the teeth or external acoustic meatuses and the nose of the head, and the placement members for placing the magnetic field generating elements for MEG and the markers for MRI measurement at the predetermined reference positions on the head by operating the positioning mechanism movably provided on the reference frame. Thus, the reference points for MRI measurement and MEG can be precisely set at the same position with relatively simple operation. ## Claims ### Claim 1 A method for setting a reference point for organic measurement, comprising the steps of: determining a relative position between a reference frame and a human head utilizing at least teeth in the head; and placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head by operating a positioning mechanism movably provided on said reference frame, wherein said magnetic field generating element for MEG is in a form of an annular body having a center hole incorporating a coil therein and said marker for MRI measurement is a smaller diameter cylindrical body with a cone-shaped tip end to be inserted through said center hole of said annular body. ### Claim 2 (depends on 1) A method as set forth in claim 1, wherein said marker for MRI measurement contains a water molecule and an anti-washable oily paint. ### Claim 3 (depends on 1) A method as set forth in claim 1, wherein said predetermined reference position of the head comprises a nasion and a tragion. ### Claim 4 A method for setting a reference point for organic measurement, comprising the steps of: determining a relative position between a reference frame and a human head utilizing at least external acoustic meatuses and a nose of the head; and placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head by operating a positioning mechanism movably provided on said reference frame, wherein said magnetic field generating element for MEG is in a form of an annular body having a center hole incorporating a coil therein and said marker for MRI measurement is a smaller diameter cylindrical body with a cone-shaped tip end to be inserted through said center hole of said annular body. ### Claim 5 (depends on 4) A method as set forth in claim 4, wherein said marker for MRI measurement contains a water molecule and an anti-washable oily paint. ### Claim 6 (depends on 4) A method as set forth in claim 4, wherein said predetermined reference position of the head comprises a nasion and a tragion. ### Claim 7 An apparatus for setting a reference point for organic measurement, comprising: a reference frame; position determining means for determining a relative position between said reference frame and a human head utilizing at least teeth in the human head; a positioning mechanism movably provided on said reference frame; and placement means provided in said positioning mechanism for placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head, wherein said magnetic field generating element for MEG is in a form of an annular body having a center hole incorporating a coil therein and said marker for MRI measurement is a smaller diameter cylindrical body with a cone-shaped tip end to be inserted through said center hole of said annular body. ### Claim 8 (depends on 7) An apparatus as set forth in claim 7, wherein said position determining means comprises a biting piece member fixed on said reference frame and bitten between the upper and lower teeth, and a chin fitting member, a head top fitting member and head side fitting members provided on said reference frame for relative movement. ### Claim 9 (depends on 8) An apparatus as set forth in claim 8, wherein said biting piece member has a ridge to be engaged between adjacent individual teeth in one of upper and lower teeth. ### Claim 10 An apparatus for setting a reference point for organic measurement, comprising: a reference frame; position determining means for determining a relative position between said reference frame and a human head utilizing at least teeth in the human head; a positioning mechanism movably provided on said reference frame; and placement means provided in said positioning mechanism for placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head, wherein said marker for MRI measurement contains a water molecule and an anti-washable oily paint. ### Claim 11 (depends on 7) An apparatus as set forth in claim 7, wherein said predetermined reference position of the head comprises a nasion and a tragion. ### Claim 12 An apparatus for setting a reference point for organic measurement comprising: a reference frame; position determining means for determining a relative position between said reference frame and a human head utilizing at least external acoustic meatuses and a nose in the human head; a positioning mechanism movably provided on said reference frame; and placement means provided in said positioning mechanism for placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head. ### Claim 13 An apparatus for organic measurement, comprising: a reference frame; position determining means for determining a relative position between said reference frame and a human head utilizing at least external acoustic meatuses and a nose in the human head; a positioning mechanism movably provided on said reference frame, and placement means provided in said positioning mechanism for placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head, wherein said position determining means comprises abutting members provided on said reference frame to be pressed onto said external acoustic meatuses, a light emitter and a light sensor provided at opposite sides of said reference frame, and a chin fitting member, a rear head fitting member and head side fitting members provided on said reference frame for relative movement. ### Claim 14 An apparatus for organic measurement, comprising: a reference frame; position determining means for determining a relative position between said reference frame and a human head utilizing at least external acoustic meatuses and a nose in the human head; a positioning mechanism movably provided on said reference frame; and placement means provided in said positioning mechanism for placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head, wherein said magnetic field generating element for MEG is in a form of an annular body having a center hole incorporating a coil therein and said marker for MRI measurement is a smaller diameter cylindrical body with a cone-shaped tip end to be inserted through said center hole of said annular body. ### Claim 15 An apparatus for organic measurement, comprising: a reference frame; position determining means for determining a relative position between said reference frame and a human head utilizing at least external acoustic meatuses and a nose in the human head; a positioning mechanism movably provided on said reference frame; and placement means provided in said positioning mechanism for placing a magnetic field generating element for MEG and a marker for MRI measurement at a predetermined reference position on the head, wherein said marker for MRI measurement contains a water molecule and an anti-washable oily paint. ### Claim 16 (depends on 13) An apparatus as set forth in claim 13, wherein said predetermined reference position of the head comprises a nasion and a tragion. ### Claim 17 (depends on 14) An apparatus as set forth in claim 14, wherein said predetermined reference position of the head comprises a nasion and a tragion. ### Claim 18 (depends on 15) An apparatus as set forth in claim 15, wherein said predetermined reference position of the head comprises a nasion and a tragion. ### Claim 19 (depends on 10) An apparatus as set forth in claim 10, wherein said predetermined reference position of the head comprises a nasion and a tragion.