# US 5,705,170 A · Herbal cellulite treatments > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 5,705,170 A - Document ID: US5705170A - Status: Granted - Kind: A - Application number: 08/547,417 - Filed: 1995-10-24 - Granted: 1998-01-06 - Earliest claimed: 1995-10-24 - Assignees: Plantech International, Inc. - Inventors: William C. Kong; Raymond Yeung - Web page: https://patentgrep.com/patent/US5705170A ## CPC - A61K 8/9789: Magnoliopsida [dicotyledons] - A61Q 19/06: for countering cellulitis - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract The invention provides a herbal cellulite treatment employing, in preferred embodiments, topical treatments, both method and cosmetic composition, wherein a refined lipophilic extract, and preferably also a refined aqueous extract of a Malvaceae plant, preferably whole Hibiscus Abelmoschus, are applied to the skin overlying cellulite-afflicted tissues. The treatments are intended to last at least four, and preferably eight or more weeks. Clinical tests show suprisingly superior results to those obtainable with aminophylline compositions. Inventive treatments can reduce thigh diameters and fatty layer thickness, as well as skin condition. In vitro tests show remarkable lipolytic properties, apparently attributable to .beta.-receptor stimulation, and valuable lipogenesis inhibition properties apparently attributable to .alpha..sub.2 -blocking. Preferred extracts show low toxicity. ## Claims ### Claim 1 A cellulite treatment composition comprising: a) a cosmetic base; b) from about 0.1 to about 10.0 percent by weight of the treatment composition of a refined aqueous extract of Hibiscus Abelmoschus rich in proteins; and c) from about 0.01 to about 10.0 percent by weight of the treatment composition of a refined lipophilic extract of Hibiscus Abelmoschus rich in sphingolipids said refined extracts being present in a relative proportion of from about 1 to about 7 parts of aqueous extract per part of lipophilic extract; said composition being topically effective when applied to cellulite afflicted tissue to reduce fatty tissue deposits. ### Claim 2 (depends on 1) A cellulite treatment composition according to claim 1, being a cosmetic composition intended for daily topical application and providing a significant measurable improvement in cellulite after at least 8 weeks of such daily topical application, said composition comprising, in proportions by weight, from about 2 to about 5 percent of said refined aqueous Hibiscus Abelmoschus extract, from about 0.5 to about 3 percent of said lipophilic Hibiscus Abelmoschus extract, said composition being effective to stimulate adipocyte lipolysis and to inhibit adipocyte fat production. ### Claim 3 A cellulite treatment composition comprising: a) a cosmetic base; b) a sufficient quantity of a refined aqueous extract of a plant species of the Malvaceae order to stimulate adipocyte lipolysis when said composition is applied topically to cellulite-afflicted tissue; and c) a sufficient quantity of a refined lipophilic extract of said plant species to inhibit adipocyte lipogenesis when said composition is applied topically to cellulite-afflicted tissue. ### Claim 4 (depends on 3) A cellulite treatment composition according to claim 3, being a cosmetic composition intended for daily topical application and providing a significant measurable improvement in cellulite after at least 8 weeks of such daily topical application, said composition comprising, in proportions by weight, from about 2 to about 5 percent of said refined aqueous Hibiscus Abelmoschus extract, from about 0.5 to about 3 percent of said lipophilic Hibiscus Abelmoschus extract, said composition being effective to stimulate adipocyte lipolysis and to inhibit adipocyte fat production. ### Claim 5 (depends on 2) A cellulite treatment composition according to claim 2, supplemented with an effective quantity of an active agent or agents to improve microcirculation, improve skin condition or reduce fluid retention. ### Claim 6 (depends on 4) A cellulite treatment composition according to claim 4 comprising one or more supplements selected from the group consisting of from about 0.1-20 percent by weight of the composition of an alpha hydroxy acid, the composition having a pH of from 3-6; a retinoid, in a proportion of from 0.1-3 percent vitamin a palmitate; from about 0.1-5 percent by weight biopeptide; from about 1.0-20.0 percent by weight of a mechanical exfoliatives; from about 1.0-5.0 percent by weight of a vasoactive ingredient; from about 1.0-5.0 of an antioxidant; and from about 2 to about 12 percent by weight of a moisturizer. ### Claim 7 A method of treating cellulite-afflicted tissue comprising the topical application of a cosmetic composition containing a sufficient quantity of a refined aqueous extract of Hibiscus Abelmoschus to stimulate adipocyte lipolysis. ### Claim 8 (depends on 7) A method according to claim 7 wherein from about 0.1 to about 10.0 percent be weight of the aqueous extract of Hibiscus Abelmoschus is applied daily for at least four weeks. ### Claim 9 (depends on 8) A method according to claim 8 wherein the aqueous extract of Hibiscus Abelmonschus is applied daily for at least eight weeks. ### Claim 10 (depends on 7) A method according to claim 7 further comprising the topical application of a sufficient quantity of a refined lipophilic extract of Hibiscus Abelmoschus to inhibit adipocyte lipogenesis when said composition is applied topically to cellulite-afflicted tissue. ### Claim 11 (depends on 10) A method according to claim 10 wherein both the aqueous and lipophilic extracts of Hibiscus Abelmoschus are applied daily for at least eight weeks in a concentration of from about 0.1 to about 10.0 percent by weight of the applied composition. ### Claim 12 A method of treating cellulite-afflicted tissue comprising the topical application of a cosmetic composition containing a sufficient quantity of a refined lipophilic extract. of Hibiscus Abelmonschus to inhibit adipocyte lipogenesis when said composition is applied topically to cellulite-afflicted tissue. ### Claim 13 (depends on 12) A method according to claim 12 wherein the lipophilic extract of Hibiscus Abelmoschus is applied daily for at least eight weeks in a proportion of from about 0.1 to about 10.0 by weight of the applied composition.