# US 5,703,127 A · Composition, dosage unit, and method for treating stomach disorders

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- Number: US 5,703,127 A
- Document ID: US5703127A
- Status: Granted
- Kind: A
- Application number: 08/591,889
- Filed: 1996-01-25
- Granted: 1997-12-30
- Earliest claimed: 1996-01-25
- Inventors: Kyoungsik Pak
- Web page: https://patentgrep.com/patent/US5703127A

## CPC

- A61K 31/198: Alpha-amino acids, e.g. alanine or edetic acid [EDTA] (betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00)
- A61K 9/2018: {Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

A dosage unit for treating stomach disorders, comprises an effective dosage of L- or DL-Methionine, and an effective dosage of a sweetener.

## Claims

### Claim 1

A composition for treating discomfort caused by heartburn, stomach pain, gastritis, reflux, or hyperacidity, consisting essentially of
L- or DL-Methionine, and
means for sweetening and for reducing the frequency and severity of undesirable side effects of the L- or DL-Methionine,
wherein said means is a sweetener,
wherein the L- or DL-Methionine is present in a range of about 25% to about 50% by weight of the composition,
wherein the sweetener is present in a range of about 50% to about 75% by weight of the composition, and
wherein the sweetener is fructose, dextrose, or sucrose.

### Claim 2 (depends on 1)

The composition of claim 1,
wherein the L- or DL-Methionine is present in an amount of about 33% by weight of the composition, and
the sweetener is present in an amount of about 67% by weight of the composition.

### Claim 3 (depends on 1)

The composition of claim 1,
wherein the L- or DL-Methionine is present in an amount of about 33% by weight of the composition, and
the sweetener is present in an amount of about 67% by weight of the composition, and
the sweetener is fructose.

### Claim 4 (depends on 1)

The composition of claim 1,
wherein the L- or DL-Methionine is present in an amount of about 40% by weight of the composition,
the sweetener is present in an amount of about 60% by weight of the composition, and
the sweetener is fructose.

### Claim 5

A dosage unit for treating discomfort caused by heartburn, stomach pain, gastritis, reflux, or hyperacidity, consisting essentially of
an effective dosage of L- or DL-Methionine, and
an effective dosage of means for sweetening and for reducing the frequency and severity of undesirable side effects of the L- or DL-Methionine, wherein said means is a sweetener,
wherein the L- or DL-Methionine is present in a range of about 25% to about 50% by weight of the composition,
wherein the sweetener is present in a range of about 50% to about 75% by weight of the composition, and
wherein the sweetener is fructose, dextrose, or sucrose.

### Claim 6 (depends on 5)

The dosage unit of claim 5,
wherein the L- or DL-Methionine is present in an amount of about 33% by weight of the dosage unit, and
the sweetener is present in an amount of about 67% by weight of the dosage unit.

### Claim 7 (depends on 5)

The dosage unit of claim 5,
wherein the L- or DL-Methionine is present in an amount of about 33% by weight of the dosage unit,
the sweetener is present in an amount of about 67% by weight of the dosage unit, and
the sweetener is fructose.

### Claim 8 (depends on 5)

The dosage unit of claim 5,
wherein the dosage of L- or DL-Methionine is present in an amount of about 1 gram, and
the dosage of the sweetener is present in a range of about 1 gram to about 3 grams.

### Claim 9 (depends on 5)

The dosage unit of claim 5,
wherein the dosage of L- or DL-Methionine is present in an amount of about 1 gram, and
the dosage of the sweetener is present in a range of about 1 gram to about 2 grams.

### Claim 10 (depends on 8)

The dosage unit of claim 8,
wherein the dosage of sweetener is 1.5 grams.

### Claim 11

A method of treating discomfort caused by heartburn, stomach pain, gastritis, reflux, or hyperacidity, consisting essentially of the steps of
providing an effective dosage of L- or DL-Methionine and an effective dosage of means for sweetening and for reducing the frequency and severity of undesirable side effects of L- or DL-Methionine,
orally ingesting the effective amount of L- or DL-Methionine and the effective amount of means for sweetening and for reducing the frequency and severity of undesirable side effects of the L- or DL-Methionine to place the L- or DL-Methionine and the means for sweetening and reducing the frequency of undesirable side effects of the L- or DL-Methionine in the stomach, and
treating the discomfort with the L- or DL-Methionine to provide relief,
wherein said means is a sweetener,
wherein the sweetener is fructose, dextrose, or sucrose,
wherein the dosage of L- or DL-Methionine is about 1 gram, and
wherein the dosage of the sweetener is in a range of about 1 gram to about 3 grams.

### Claim 12 (depends on 11)

The method of claim 11, wherein the L- or DL-Methionine is mixed into an effective amount of water to form a mixture before ingesting the L- or DL-Methionine.

### Claim 13 (depends on 11)

The method of claim 11, wherein a sufficient amount of food is ingested to ensure that the stomach is not empty before ingesting the L- or DL-Methionine.

### Claim 14 (depends on 11)

The method of claim 11, wherein
the L- or DL-Methionine and sweetener are mixed into an effective amount of water to form a mixture before ingesting the L- or DL-Methionine and sweetener, and
wherein the amount of water is about 2 ounces.

### Claim 15 (depends on 14)

The method of claim 14,
wherein the dosage of sweetener is 1.5 grams.
