# US 5,700,354 A · Paper strengthened with solubilized collagen and method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 5,700,354 A - Document ID: US5700354A - Status: Granted - Kind: A - Application number: 08/479,175 - Filed: 1995-06-07 - Granted: 1997-12-23 - Earliest claimed: 1993-06-16 - Assignees: Ranpak Corp. - Inventors: Kevin M. Virnelson; Kenneth E. Hughes; David C. Masterson; David J. Fink; Barbara A. Metz; Gordon E. Pickett; Paul M. Gemmer; Richard S. Brody - Web page: https://patentgrep.com/patent/US5700354A ## CPC - C07K 14/78: Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG] - D21H 17/22: Proteins - A61K 38/00: Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) - D21H 11/14: Secondary fibres (working-up waste paper D21C5/02) - D21H 21/18: Reinforcing agents - C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00) - D21H: PULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) ## Abstract A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction of the cellulosic pulp slurry and solubilized collagen; forming the interacted cellulosic pulp slurry and solubilized collagen into a sheet; and drying the sheet; also, a method for using solubilized collagen for strengthening paper by mixing the solubilized collagen with a cellulosic pulp slurry; and making a cellulosic pulp product from the mixture and drying. ## Claims ### Claim 1 A collagen strengthened cellulosic product made by a process comprising: a. adding soluble collagen solids having a number average molecular weight of at least 300,000 daltons to a cellulosic pulp slurry in a paper machine in an amount of about 0.2% to about 1.0% soluble collagen solids as compared to pulp solids and at a pH of addition of about 4.0 to 7.0 based on the final pulp slurry pH; b. mixing said soluble collagen and said slurry to form a collagen/pulp slurry; c. forming a cellulosic product of desired shape from said collagen/pulp slurry; and d. drying said product. ### Claim 2 (depends on 1) A product as set forth in claim 1, wherein said cellulosic pulp slurry comprises short pulp fibers. ### Claim 3 (depends on 2) A product as set forth in claim 2, wherein said pulp slurry comprises about 80% to about 95% ONP. ### Claim 4 (depends on 3) A product as set forth in claim 3, wherein said pulp slurry comprises greater than 90% ONP. ### Claim 5 (depends on 1) A product as set forth in claim 1, wherein said ONP comprises newsblank mixed with stronger fibers. ### Claim 6 (depends on 2) A product as set forth in claim 2, wherein said pulp slurry comprises about 90% ONP and about 10% OCC. ### Claim 7 (depends on 2) A product as set forth in claim 2, wherein said short pulp fibers comprises eucalyptus fiber. ### Claim 8 A collagen strengthened cellulosic product made by a process comprising: a. adding soluble collagen solids having a number average molecular weight of at least 300,000 daltons to a cellulosic pulp slurry in a paper machine, wherein said soluble collagen is added in an amount of about 0.5% soluble collagen solids as compared to pulp solids and said cellulosic pulp slurry is comprised of about 90% ONP fiber and about 10% OCC, and said addition is at a pH of addition of about 6.0 based on the final pulp slurry pH; b. mixing said soluble collagen and said slurry to form a collagen/pulp slurry; c. forming a cellulosic product of desired shape from said collagen/pulp slurry; and d. drying said product. ### Claim 9 (depends on 8) A product as set forth in claim 8, wherein said cellulostic product is a cellulosic sheet. ### Claim 10 (depends on 8) A product as set forth in claim 8, wherein machine direction tensile strength of the resultant cellulosic sheet is about 15% to about 20% greater than that obtained with normally employed synthetic polymers employed as retention aids.