# US 5,699,807 A · Blood pressure measuring system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 5,699,807 A - Document ID: US5699807A - Status: Granted - Kind: A - Application number: 08/507,709 - Filed: 1995-07-26 - Granted: 1997-12-23 - Earliest claimed: 1994-07-26 - Assignees: Nihon Kohden Corporation - Inventors: Jun Motogi; Yoshio Sakai; Sunao Takeda - Web page: https://patentgrep.com/patent/US5699807A ## CPC - A61B 5/02116: {of pulse wave amplitude (A61B5/02225 takes precedence)} - A61B 5/022: by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers - A61B 5/7239: {using differentiation including higher order derivatives} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A pressure sensor gathers discrete data representing the pulse amplitude of a pulse wave signal when a cuff pressure is increased and decreased. A RAM stores the discrete data of the pulse amplitude. A CPU processes the discrete data by using a spline function, to thereby generate the data representative of a smooth continuous line passing by points of the pulse amplitude of the discrete data. This process reduces a variation of the pulse amplitude of a pulse wave signal, to thereby minimize a variation of the blood pressure values. An inflection point of the smooth continuous line is used as a diastolic blood pressure value. ## Claims ### Claim 1 A blood pressure measuring system comprising: blood pressure measuring means for measuring a blood pressure by using a pulse wave signal representative of a pulsation of an artery of a living body, said blood pressure measuring means comprising: pulse wave detecting means for continuously detecting a pulse wave of said pulse wave signal; storage means for storing data representative of a continuous pulse wave that is outputted from said pulse wave detecting means, said data including discrete data of a pulse amplitude of said pulse wave; data processing means for reading discrete data of said pulse amplitude of said pulse wave from said storage means, and for processing said discrete data by using a spline function to generate data representative of a smooth continuous line; and blood pressure calculating means for calculating a blood pressure value on the basis of said data of said smooth continuous line, said blood pressure calculating means including detecting means for detecting a cuff pressure being treated as a diastolic blood pressure at an inflection point of said data representative of said smooth continuous line. ### Claim 2 (depends on 1) The blood pressure measuring system according to claim 1, further comprising: weight processing means for applying a weight processing to said discrete data of said pulse amplitude of said pulse wave that is outputted from said pulse wave detecting means. ### Claim 3 (depends on 1) A blood pressure measuring system as claimed in claim 1, wherein said detecting means performs a second order differentiation on said data representative of said smooth continuous line to achieve said inflection point. ### Claim 4 A blood pressure measuring method for measuring a blood pressure by using a pulse wave signal representative of a pulsation of an artery of a living body, comprising the steps of continuously detecting a pulse wave of said pulse wave signal; storing data representative of a continuous pulse wave, said data including discrete data of a pulse amplitude of said pulse wave; reading said discrete data of said pulse amplitude of said pulse wave; processing said discrete data by using a spline function to generate data representative of a smooth continuous line; calculating a blood pressure value on the basis of said data of said smooth continuous line; and detecting a cuff pressure being treated as a diastolic blood pressure at an inflection point of said data representative of said smooth continuous line. ### Claim 5 (depends on 4) The blood pressure measuring method according to claim 4, further comprising: applying a weight processing to said discrete data of said pulse amplitude of said pulse wave. ### Claim 6 (depends on 4) A blood pressure measuring method as claimed in claim 4, wherein said detecting step includes the step of performing a second order differentiation on said data represented of said smooth continuous line to achieve said inflection point. ### Claim 7 A blood pressure measuring system comprising a blood pressure measuring circuit for measuring a blood pressure by using a pulse wave signal representative of a pulsation of an artery of a living body, said blood pressure measuring means comprising: pulse wave detecting means for continuously detecting a pulse wave of said pulse wave signal; storage means for storing data representative of a continuous pulse wave that is outputted from said pulse wave detecting means, said data including discrete data of a pulse amplitude of said pulse wave; correcting means for reading discrete data of said pulse amplitude of said pulse wave from said storage means, and for correcting said discrete data by using a predetermined function to generate corrected data of said pulse amplitude, weighting coefficient determining means for determining weighting coefficient on the basis of a ratio defined by said data read from said storage means and said corrected data, data processing means for weighting said data read from said storage means by said weighting coefficient, and for processing the weighted data using a spline function to generate data representative of a smooth continuous line; and blood pressure calculating means for calculating a blood pressure value on the basis of said smooth continuous line. ### Claim 8 (depends on 7) The blood pressure measuring system according to claim 7, wherein said correcting means includes spline function processing means to generate correcting data by using a spline function. ### Claim 9 (depends on 7) The blood pressure measuring system according to claim 7, wherein said weighting coefficient determining means comprises: subtraction calculating means for subtracting said corrected data from said data read from said storage means, selecting means for selecting data for weighting on the basis of a ratio defined by said subtracted data provided by said subtraction calculating means and said data read from said storage means; and wherein said data processing means weights data selected by said selecting means by said weighting coefficient. ### Claim 10 (depends on 9) The blood pressure measuring system according to claim 9, wherein said weighting coefficient is 0.5, and wherein said ratio ranges from 10% to 30%. ### Claim 11 (depends on 7) The blood pressure measuring system according to claim 7, wherein said data processing means uses a (2M-1)-th order spline function for generating data representative of a smooth continuous line. ### Claim 12 (depends on 7) The blood pressure measuring system according to claim 7, wherein said blood pressure calculating means includes detecting means for detecting a cuff pressure being treated as a diastolic blood pressure at inflection of said data representative of said smooth continuous line. ### Claim 13 A method of measuring a blood pressure by using a pulse wave signal representative of a pulsation of an artery of a living body, said method comprising the steps of: continuously detecting a pulse wave of said pulse wave signal; storing data representative of said pulse wave being continuously detected, said data including discrete data of a pulse amplitude of said pulse wave; reading said discrete data of said pulse amplitude of said pulse wave from said stored data; correcting said discrete data by using a predetermined function to generate corrected data of said pulse amplitude; determining a weighting coefficient on the basis of a ratio defined by said data read from said stored data and said corrected data; weighting said data read from said stored data using said weighting coefficient to generate weighted data; processing the weighted data using a spline function to generate data representative of a smooth continuous line; and calculating a blood pressure value on the basis of said smooth continuous line. ### Claim 14 (depends on 13) The method according to claim 13, wherein said predetermined function is a spline function. ### Claim 15 (depends on 13) The method according to claim 13, wherein said step of determining further comprises the steps of: subtracting said corrected data from said data read from said stored data to produce subtracted data, and selecting data for weighting on the basis of a ratio defined by said subtracted data and data read during said step of reading; and wherein said step of weighting, data selected during said step of selecting is weighted by said weighting coefficient. ### Claim 16 (depends on 15) The method according to claim 15, wherein said weighting coefficient is 0.5, and wherein said ratio ranges from 10% to 30%. ### Claim 17 (depends on 13) The method according to claim 13, wherein said spline function is a (2M-1)-th order spline function.