Malonic acid derivatives having antiadhesive properties

A compound of formula I ##STR20## in which R.sup.1, R.sup.2 and R.sup.3 independently of one another are H, (CH.sub.2).sub.m X or CH.sub.2 O(CH.sub.2).sub.m X.sup.1 or

• R.sup.1 and R.sup.2 together form a six-membered carbo- or heterocycle having at least one substituent selected from the group consisting of R.sup.4, R.sup.5 and R.sup.6 and
• A and B independently of one another are O, S, NH, HN--CO, OC--NH, O--CO, OC--O, NH--CO--O, O--CO--NH, S--CO, SC--O, O--CS--S, S--CS--O, NH--CS--S, S--CS--NH or CH.sub.2 and
• Z is a pyranose, a furanose, an open-chain polyalcohol or Y-X.sup.6,
• Y is --O--(CX.sub.2 X.sup.3).sub.n, --(CX.sup.2 X.sup.3).sub.n, --(CX.sup.2 R.sup.7).sub.n --, --(CR.sup.7 R.sup.8).sub.n --, --CH.sub.2 --(CX.sup.2 X.sup.3).sup.-.sub.n or a saturated or
• unsaturated, six-membered carbocycle or heterocycle having at least one substituent R.sup.9, or Y is a pair of said carbocycle or said heterocycle and a chain, wherein said chain is selected from the group consisting of --O--(CX.sup.2 X.sup.3).sub.n, --(CX.sup.2 X.sup.3).sub.n --, --(CX.sup.2 R.sup.7).sub.n --, and --(CR.sup.7 R.sup.8).sub.n --, where
• R.sup.4, R.sup.5 and R.sup.6 independently of one another are H, OH, (CH.sub.2).sub.q X.sup.4, CH.sub.2 O(CH.sub.2).sub.q X.sup.5 or HNC(O)CH.sub.3 and
• R.sup.7, R.sup.8 and R.sup.9 independently of one another are H, OH, --O--(CH.sub.2).sub.q X.sup.4 or CH.sub.2 O(CH.sub.2).sub.q X.sup.5 and
• X, X.sup.1, X.sup.2, X.sup.3, X.sup.4 and X.sup.5 independently of one another are H, NH.sub.2, COOH, OH, CH.sub.2 OH, CH.sub.2 NH.sub.2, C.sub.1 -C.sub.20 -alkyl or C.sub.6 -C.sub.10 -aryl and
• X.sup.6 is OH or ##STR21## and m, n and q independently of one another is an integer from 1 to 20.