Enhancement of fertilization capability of oocytes
AssigneesGenentech, Inc., Oregon Regional Primate Research Center
InventorsBaha M. Alak, Richard L. Stouffer, Don P. Wolf, Teresa K. Woodruff
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Abstract
A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. After the culturing step, the oocytes can be fertilized. The oocytes are suitably cryopreserved and thawed before the culturing step.
Claims1
A composition comprising human or non-human primate oocytes and a culture medium which comprises at least about 0.01 ng/ml of human activin and at least about 0.01 ng/ml of human inhibin.
Dependencies are inferred from the claim text.