Back to results
US 5,693,335 AGranted
Skin permeation enhancer composition for use with sex steroids
AssigneeCygnus, Inc.
InventorsJun Xia, Janan Jona, Chia-Ming Chiang
Life of this patent
Estimating the term…
Abstract
A combination permeation enhancer for increasing the permeability of skin to sex steroids such as estrogens and progestogens comprising a polyhydric thioalcohol of 2 to 6 carbon atoms having at least one mercapto group and at least one hydroxy group and an aliphatic carboxylic acid of 8 to 24 carbon atoms or an ester thereof.
Claims14
A matrix for use in transdermally administering a sex steroid consisting essentially of a mixture of
- a) a pressure-sensitive adhesive;
- b) a sex steroid;
- and
- c) a skin permeation enhancer consisting essentially of a mixture of:
- (i) a polyhydric thioalcohol of 2 to 6 carbon atoms having at least one mercapto group and at least one hydroxy group;
- and
- (ii) an aliphatic carboxylic acid of 8 to 24 carbon atoms or an ester of said acid.
4 more elements
Dependencies are inferred from the claim text.