Use of topical azathioprine to treat inflammatory bowel disorders
AssigneeMayo Foundation for Medical Education and Research
InventorWilliam J. Sandborn
Life of this patent
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Abstract
A method is provided to treat inflammatory bowel disease by topically administering to the colon an effective amount of azathioprine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.
Claims5
A therapeutic method of treating inflammatory bowel disease comprising topically administering to the colon of a patient in need of such treatment by rectal enema or by means of an orally ingested unit dosage form comprising an effective amount of enterically coated azathioprine which is released from the dosage form in the terminal portion of the ileum and in the colon of said patient, an amount of azathioprine effective to relieve the symptoms of said inflammatory bowel disease.
Dependencies are inferred from the claim text.