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US 5,691,206 AGranted
Method and device for solid phase microextraction and desorption
OwnerJanusz B. Pawliszyninventor
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OwnerJanusz B. Pawliszyninventor
Estimating the term…
A device for carrying out solid phase microextraction is a fiber contained in a syringe. The fiber can be solid or hollow. The syringe has a barrel and a plunger slidable within the barrel, the plunger having a handle extending from one end of the barrel. A hollow needle extends from an end of the barrel opposite to the plunger. The fiber is contained in the needle. When the plunger is depressed, the fiber extends beyond a free end of the needle and when the plunger is in a withdrawn position, the fiber is located within the needle. The syringe protects the fiber from damage. When it is desired to analyze a sample in a bottle having a septum, the needle is inserted through the septum and the plunger is depressed so that the fiber will extend into the sample. After one or two minutes, the plunger is moved to the withdrawn position so that the fiber will return to the needle and the syringe is withdrawn from the sample bottle. The syringe is then inserted through a septum in a gas injection port of a gas chromatograph. The plunger is again depressed so that the fiber will extend into the gas chromatograph and an analysis of the components on the fiber is carried out. Then, the plunger is moved to the withdrawn and the syringe is withdrawn from the injection port. Previously, samples were analyzed using liquid-liquid extraction or using cartridges. Both of these methods are relatively expensive and time consuming. Both of these methods also require the use of solvents which can be difficult and expensive to dispose of.
A device for carrying out solid phase microextraction of components contained in a fluid carrier, said device being characterized by, in combination, a fiber and a housing surrounding said fiber, said fiber having means for selectively extracting at least one component in said fluid carrier, said fiber being mounted to a movable part in said housing so that said fiber is movable longitudinally within said housing, said movable part being able to successively expose a length of said fiber outside of said housing to said carrier and retract said fiber into said housing out of contact with said carrier.
A method of carrying out solid phase microextraction and analysis with components contained in a carrier using a fiber contained in a housing, said housing having access means so that said carrier can be brought into contact with said fiber, said method comprising the steps of choosing either the fiber or a coating for the fiber based on selectivity of the fiber or the coating for at least one component contained in said carrier, contacting said fiber with said carrier for a sufficient time to allow chemical extraction to occur of said at least one component, ending said contact and placing the fiber in a suitable analytical instrument in such a manner that desorption occurs with respect to the at least one component extracted from said carrier by said fiber.
A method of carrying out solid phase microextraction and analysis, with components contained in a carrier, using a fiber, said method comprising the steps of choosing either the fiber or a coating for the fiber based on selectivity of the fiber or the coating for at least on component contained in said carrier, placing said fiber in contact with said carrier containing said components for a sufficient period of time for chemical extraction to occur of said at least one component, subsequently removing said fiber from said carrier and placing the fiber into a suitable analytical instrument and carrying out thermal desorption with respect to the at least one component extracted from said carrier by said fiber.
Dependencies are inferred from the claim text.