Use of sabeluzole in chronic neurodegenerative diseases
AssigneeJanssen Pharmaceutica NV
InventorsGilbert Henri Camiel Clincke, Luc Remi Mathilde Tritsmans, Hugo Alfons Gabriel Geerts
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Abstract
The present invention is concerned with the use of sabeluzole for the manufacture of a medicament for the treatment of patients suffering from chronic neuro-degenerative diseases such as dementia of the Alzheimer type (DAT) or Alzheimer's disease, amyotrophic lateral sclerosis (ALS), dementia associated with Parkinson's disease and related diseases which are characterized by progressive dementia.
Claims1
A process of inducing in neuronal cells the expression of epitopes associated with aberrantly phosphorylated tau-protein, which method comprises contacting said cells with a medium conditioned from serum-starved cells for several days and having acquired cytotoxic activity.
Dependencies are inferred from the claim text.