Oral composition containing a mixed surfactant system for promoting antibacterial compound uptake on dental tissue
AssigneeColgate-Palmolive Company
InventorsYelloji Rao K. Mirajkar, John Afflitto, Nuran Nabi, Abdul Gaffar
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Abstract
An oral composition comprising in an orally acceptable vehicle, an effective antiplaque amount of an halogenated diphenyl ether or phenolic antibacterial compound, and an amount of an mixed anionic/nonionic surfactant system at weight ratios of about 14:1 to 9:1 which ratios are effective to increase the uptake of the antibacterial compound to dental tissue so as to enhance the therapeutic efficacy of the administered antibacterial compound.
Claims24
An aqueous oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein, the composition comprising in an orally acceptable vehicle containing less than 60% by weight water, an effective therapeutic amount of a halogenated diphenyl ether or phenolic antibacterial compound and a mixture of an anionic and a nonionic surfactants at a weight ratio of about 14:1 to about 9:1.
A method for the treatment and prevention of bacterial plaque accumulation on teeth which comprises preparing an aqueous oral composition comprising an orally acceptable vehicle containing less than 60% by weight water, an effective therapeutic amount of a halogenated diphenyl ether or phenolic antibacterial compound and a mixture of anionic and nonionic surfactants at a weight ratio of about 14:1 to about 9:1, and then administering the composition to the oral cavity, whereby, the antibacterial compound exhibits increased uptake to dental tissue.
Dependencies are inferred from the claim text.