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US 5,688,917 AGranted
Process for functional expression of the para cation channel
AssigneeMerck & Co., Inc.
InventorsJoseph P. Arena, Guoping Feng, Linda M. Hall, Ken Liu, Leonardus H. T. Van Der Ploeg, Peiyi Wang, Jeffrey W. Warmke
Life of this patent
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Abstract
DNAs encoding voltage-activated cation channels have been cloned and characterized. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells.
Claims1
A recombinant biologically active voltage activated cation channel in a membrane, said channel comprising an alpha subunit and a beta subunit wherein said alpha subunit is para and said beta subunit is tipE.
Dependencies are inferred from the claim text.