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US 5,688,900 AGranted
Absorbable polyalkylene diglycolates
AssigneeEthicon, Inc.
InventorsKevin Cooper, Angelo G. Scopelianos
Life of this patent
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Abstract
Absorbable polymers and blends of poly(alkylene diglycolate)s and aliphatic polyesters based on lactone monomers such as lactide, glycolide, 68 -caprolactone, p-dioxanone, and trimethylene carbonate are described. The polymers and blends exhibit a broad range of properties, useful in a variety of medical devices.
Claims4
An absorbable, biocompatible poly(alkylene diglycolate) consisting of the reaction product of:
- an acid or ester of diglycolic acid;
- and,
- an aliphatic, saturated alcohol selected from the group consisting of glycerol, pentaerythitol, trimethylolpropane, hydroxyl terminated poly(ethylene glycol)s, ethylene glycol, 1,2-propanediol, 1,3-propanediol, 1,4-butylene glycol, dipropylene glycol, 1,5-pentanediol, 1,6-hexanediol, 1,7-heptanediol, and 1,8-octanediol,
- wherein the poly(alkylene diglycolate) comprises about 45 mole percent to about 90 mole percent of repeating units with aliphatic saturated tri-, tetra-alcohols, and hydroxyl terminated poly(ethylene glycol)s, and wherein the balance of the poly(alkylene diglycolate) comprises repeating units with diol alcohols.
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An absorbable device for use in medical applications, the medical device comprising a poly(alkylene diglycolate), wherein said poly(alkylene diglycolate) consists of the reaction product of:
- a) an acid or ester of diglycolic acid;
- and,
- b) an aliphatic, saturated alcohol selected from the group consisting of glycerol, pentaerythitol, trimethylolpropane, hydroxyl terminated poly(ethylene glycol)s, ethylene glycol, 1,2-propanediol, 1,3-propanediol, 1,4-butylene glycol, dipropylene glycol, 1,5-pentanediol, 1,6-hexanediol, 1,7-heptanediol, and 1,8-octanediol,
- wherein the poly(alkylene diglycolate) comprises about 40 mole percent to about 90 mole percent of repeating units with aliphatic saturated tri-, tetra-alcohols, and hydroxyl terminated poly(ethylene glycol)s, and wherein the balance of the poly(alkylene diglycolate) comprises repeating units with diol alcohols.
1 more element
Dependencies are inferred from the claim text.