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US 5,688,816 AGranted
Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
AssigneeHoechst Marion Roussel, Inc.
InventorsRichard C. Effland, Larry Davis, Gordon E. Olsen
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Abstract
This invention relates to compounds of the formula ##STR1## where R.sub.1 -R.sub.6, X and Y are as defined in the specification, which are useful for the treatment of various memory dysfunctions characterized by a cholinergic deficit and thus may be indicated in the treatment of Alzheimer's disease.
Claims1
A compound of the formula ##STR12## where R1 is hydrogen, loweralkyl, loweralkenyl or loweralkynyl;
- R2 is hydrogen, loweralkyl, loweralkenyl, formyl or cyano;
- R3 is hydrogen or loweralkyl;
- R4 is heteroaryl or heteroarylloweralkyl, wherein the heteroaryl group is selected from the group consisting of furanyl, thienyl, pyrrolyl or pyridinyl;
- X and Y are independently hydrogen, nitro, amino, halogen, loweralkyl, loweralkoxy or hydroxy;
- or the pharmaceutically acceptable acid addition salts thereof, and where applicable, the geometric and optical isomers and racemic mixtures thereof.
2 more elements
Dependencies are inferred from the claim text.