Back to results
US 5,688,771 AGranted
Lipophilic oligopeptides with immunomodulating activity
AssigneeBioChem Pharma Inc.
InventorsChristopher Penney, Boulos Zacharie
Life of this patent
Estimating the term…
Abstract
New, small and structurally simple immunomodulating oligopeptides are disclosed. The oligopeptides of this invention possess a long, lipophilic alkyl chain. These immunomodulating oligopeptides can be used in conjunction with anti-viral or anti-cancer agents in the treatment of human and animal diseases. Processes for the syntheses of immunomodulating chemicals are also disclosed.
Claims14
An oligopeptide of formula (II):
- ##STR25## wherein:
- p is an integer selected from zero to four;
- each Z is independently C.dbd.O or C.dbd.S;
- each r is independently an integer selected from zero to two;
- Y is selected from the group consisting of --O--, --S-- and --NH--;
- n is an integer selected from eleven to nineteen;
- X is NH.sub.2, OH or OCH.sub.3 ;
- HA, if present, is an organic or inorganic acid which will form a physiologically acceptable salt with said oligopeptide;
- and
- Q is C.sub.1 -C.sub.4 branched or unbranched alkyl, phenyl, benzyl, hydroxymethyl or a side chain from any naturally occurring amino acid.
7 more elements
The oligopeptide octadecyl D-alanyl L-glutamine.
Dependencies are inferred from the claim text.