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US 5,688,678 AGranted
DNA encoding and methods for producing BMP-8 proteins
AssigneeGenetics Institute, Inc.
InventorsRodney M. Hewick, Jack H. Wang, John M. Wozney, Anthony J. Celeste
Life of this patent
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Abstract
Purified cartilage and/or bone inductive proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
Claims4
An isolated DNA sequence selected from the group consisting of
- (a) the nucleotide sequence set forth in SEQ ID NO:
- 13 comprising nucleotide #8 to #850;
- and
- (b) nucleotide sequences which encode the amino acid sequence comprising amino acid #139 to #142 of SEQ ID NO:
- 14.
2 more elements
An isolated DNA sequence selected from the group consisting of
- (a) the nucleotide sequence set forth in SEQ ID NO:
- 13 comprising nucelotide #434 to #850;
- and
- (b) nucleotide sequences which encode the amino acid sequence comprising amino acid #4 to #142 of SEQ ID NO:
- 14.
2 more elements
Dependencies are inferred from the claim text.