Gustducin polynucleotides, vectors, host cells and recombinant methods
AssigneeLinguagen Corporation
InventorRobert F. Margolskee
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Abstract
A novel taste cell specific guanine nucleotide binding protein, gustducin, is disclosed as well as polynucleotide sequences encoding the .alpha. subunit of gustducin. Also disclosed are methods of modifying taste involving agents that inhibit or activate the gustducin .alpha. subunit, methods for identifying such taste modifying agents and various taste modifying agents.
Claims5
A purified and isolated gustducin .alpha. subunit polynucleotide consisting of the nucleotide sequence set out in SEQ ID NO:
- 11.
A purified and isolated polynucleotide encoding a gustducin .alpha. subunit polypeptide consisting of the amino acid sequence set out in SEQ ID NO:
- 12.
Dependencies are inferred from the claim text.