Back to results
US 5,688,659 AGranted
Streptolysin O peptide antigens and methods for the determination of streptolysin antibodies
AssigneeBoehringer Mannheim GmbH
InventorsChristoph Seidel, Geoffrey Burns, Wolf-Dieter Engel
Life of this patent
Estimating the term…
Abstract
SLO peptide antigens are described. These peptide antigens are suitable for the determination of SLO antibodies, as immunogens for the production of antibodies against SLO and as vaccines for the production of vaccines against SLO.
Claims3
A method for the determination of anti-SLO antibodies, comprising the steps of
- incubating a sample with a peptide antigen under conditions which enable the formation of an antibody-antigen complex, wherein said peptide antigen comprises at least a part of one amino acid sequence selected from the group consisting of SEQ ID NO:
- 2 and SEQ ID NO:
- 5, wherein said part of the amino acid sequence is at least 4 amino acids in length, and wherein said antigen has a negative band between 190 and 200 nm in the CD spectrum and
- determining any anti-SLO antibodies bound to the peptide antigen.
1 more element
Dependencies are inferred from the claim text.