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US 5,688,658 AGranted
Detection of prostate-specific antigen in breast tumors
AssigneeNordion International Inc.
InventorEleftherios P. Diamandis
Life of this patent
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Abstract
This invention relates to the detection of prostate-specific antigen (PSA) in female breast tumor extract as a prognostic or predictive indicator for breast carcinoma. The presence of prostate-specific antigen in breast tumors is associated with earlier disease stage, younger women and better survival. PSA is associated with tumors which have estrogen and/or progesteron receptors.
Claims7
A method for detecting the presence of prostate specific antigen (PSA) as a prognostic or predictive indicator of breast carcinoma in female breast tumor tissue, said method comprising:
- i) conducting a biological assay for the presence of PSA in a sample of breast tumor tissue, said assay being capable of detecting a concentration of at least as low as 0.03 ng of PSA per mg of total protein in the sample;
- and
- ii) upon detecting PSA in said sample classifying said sample as PSA positive which indicates a favorable prognosis for breast cancer.
Dependencies are inferred from the claim text.