Cephalosporines
AssigneeBiochemie Gesellschaft
InventorsJohannes Ludescher, Hubert Sturm, Josef Wieser
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Abstract
The invention relates to a new economical and simple process, using a new intermediate compound, for the production of 3'-substituted 7-amino-3-propenyl-4-cephem-carboxylic acid derivatives of formula ##STR1## wherein R is hydrogen, a negative charge or a silyl protecting group, R.sub.o is hydrogen or methoxy, R.sub.1 is hydrogen or a silyl protecting group and X is the radical of a nucleophile, and their acid addition salts.
Claims4
A compound of formula IX ##STR11## wherein R.sub.o is hydrogen or methoxy, and each R.sub.6 is trimethylsilyl, triethylsilyl, tri-n-propylsilyl, tri-n-butylsilyl, methyldiethylsilyl, dimethylethylsilyl, phenyldimethylsilyl, tert-butyldiphenylsilyl, tert-butyldimethylsilyl, or triphenylsilyl.
7-Trimethylsilylamino-3-(3-iodo1propen1-yl)-3-cephem-4-carboxylic acid trimethylsilyl ester.
Dependencies are inferred from the claim text.