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US 5,686,580 AGranted
Antibodies having binding specificity to ShET2, an enterotoxin of Shigella flexneri 2A
AssigneeUniversity of Maryland at Baltimore
InventorsAlessio Fasano, Myron M. Levine, James P. Nataro, Fernando Noriega
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Abstract
Substantially pure enterotoxins of Shigella flexneri 2a are described, along with a method for obtaining the same, antibodies having binding specificity to the enterotoxins and a method for use of the enterotoxins to develop a non-reactogenic Shigella flexneri 2a vaccine candidate.
Claims2
An antibody having binding specificity to ShET2 enterotoxin of Shigella flexneri 2a which consists of the amino acid sequence encoded by the DNA of SEQ ID NO:2.
Dependencies are inferred from the claim text.