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US 5,686,491 AGranted
Infant formula
AssigneeSigma-Tau Pharmaceuticals, Inc.
InventorGeoffrey Sherwood
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AssigneeSigma-Tau Pharmaceuticals, Inc.
InventorGeoffrey Sherwood
Estimating the term…
The present invention provides an infant formula for infants with metabolic disorders in fatty acid catabolism such as medium-chain acyl-CoA dehydrogenase deficiency (MCAD), long-chain acyl-CoA dehydrogenase deficiency (LCAD), short-chain acyl-CoA dehydrogenase deficiency (SCAD), multiple acyl-CoA dehydrogenase deficiency (MADD), Sudden Infant Death Syndrome (SIDS) and failure to thrive syndrome. The present invention also provides an assay for diagnosing children and infants with metabolic disorders such as failure to thrive syndrome; a method for treating failure to thrive syndrome; and a process for normalizing the lipid content of the mitochondrial membrane. In particular, the present invention provides an infant formula containing 90-130 cals/Kg which comprises (a) 2.5-3.5 g/Kg protein; (b) carbohydrate; (c) fat; and (d) .gtoreq.500 mg carnitine, wherein the ratio of carbohydrate to fat is greater than or equal to 60:40.
An infant formula, comprising 90-130 cal/Kg, wherein said formula comprises:
An infant formula containing 110 calories/Kg which comprises:
A method of treating Failure to Thrive Syndrome (FTTS), comprising administering to a patient in need thereof a formula which contains 90-130 cals/Kg and comprises:
A method for returning the lipid content of the mitochondrial membrane to homeostasis comprising:
An infant formula, comprising 90-130 cal/Kg, wherein said formula comprises .gtoreq.500 mg carnitine and 2.3-3.5 g/Kg protein and the remaining calories are provided as carbohydrate and fat;
Dependencies are inferred from the claim text.