Treatment of cataract with 15-keto-prostaglandin compounds

A method for treatment of cataract which comprises administering to a subject in need of such treatment, a 15-ketoprostaglandin compound in an amount effective in treatment of cataract, wherein said compound is of formula (I):

• ##STR6## wherein X and Y are hydrogen, hydroxy, halo, lower alkyl, hydroxy(lower)alkyl or oxo, with the proviso that at least one of X and Y is a group other than hydrogen, the 5-membered ring Q may have at least one double bond, Z is hydrogen or halo, A is --CH.sub.2 --OH, --COCH.sub.2 OH, --COOH, salt thereof, ester thereof or amide thereof, B is --CH.sub.2 --CH.sub.2 --, R.sub.1 is a bivalent saturated or unsaturated, lower or medium aliphatic hydrocarbon residue which is unsubstituted or substituted with halo, oxo or aryl and R.sub.2 is a saturated or unsaturated, lower or medium aliphatic hydrocarbon residue which is unsubstituted or substituted with halo, hydroxy, oxo, lower alkoxy, lower alkanoyloxy, cyclo(lower)alkyl, aryl or aryloxy.