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US 5,686,483 AGranted
Aminoalkyloximes
AssigneeHoechst Marion Roussel, Inc.
InventorsGregory M. Shutske, Brian S. Freed, John D. Tomer, IV, R. Richard L. Hamer
Life of this patent
Estimating the term…
Abstract
Novel aminoalkyloximes, precursors and processes for the preparation thereof, and methods of treating depression and obsessive compulsive disorders are described.
Claims5
A compound of the formula
- wherein:
- a. X is hydrogen, loweralkyl, loweralkoxy, halogen, trifluoromethyl, or a group of the formula ##STR20## wherein Y is hydrogen or loweralkyl, and p is 1 or 2;
- b. A is a group of the formula ##STR21## wherein r is 1, and B is a group of the formula ##STR22## wherein X and p are as above or B is a group of the formula ##STR23## wherein R.sup.3 or is hydrogen or loweralkyl and X and p are as above;
- c. R.sup.1 and R.sup.2 are independently hydrogen or loweralkyl or R.sup.1 and R.sup.2 taken together with the nitrogen atom to which they are attached form a group of the formula ##STR24## wherein W is CH.sub.2, O or S, r is 1, 2, or 3, and s is 1,2, or 3;
- d. m and n are 2 to 6, inclusive, the geometric and optical isomers thereof;
- or the pharmaceutically acceptable salts thereof.
3 more elements
Dependencies are inferred from the claim text.