Quinazoline deriviates for treating peptic ulcer
AssigneeYuhan Corporation
InventorsJong Wook Lee, Jeong Seok Chae, Chang Seop Kim, Jae Kyu Kim, Dae Sung Lim, Jeong Won Lee, Moon Kyu Shon, Dae Woong Jo
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Abstract
A quinazoline derivative represented by formula(I) or a pharmaceutically acceptable salt thereof is useful for the treatment of peptic ulcer, wherein: ##STR1## R.sub.1 and R.sub.2 are each hydrogen or a C.sub.1 -C.sub.4 alkyl group; R.sub.3 is hydrogen or a halogen; R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9, which may be the same or different, are each hydrogen, a C.sub.1 -C.sub.4 alkyl group, a cyclopropyl group, or a C.sub.1 -C.sub.4 alkyl group substituted with a halogen; and R.sub.10 is a methoxy group.
Claims9
A quinazoline derivative represented by formula(I) and a pharmaceutically acceptable salt thereof:
- ##STR4## wherein R.sub.1 and R.sub.2 are each hydrogen or a C.sub.1 -C.sub.4 alkyl group;
- R.sub.3 is hydrogen or a halogen;
- R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9, which may be the same or different, are each hydrogen, a C.sub.1 -C.sub.4 alkyl group, a cyclopropyl group, or a C.sub.1 -C.sub.4 alkyl group substituted with a halogen;
- and
- R.sub.10 is a methoxy group.
Dependencies are inferred from the claim text.