Norbornane type ester hydrolase
AssigneeShionogi & Co., Ltd.
InventorsBunji Kageyama, Masanori Nakae, Shigeo Yagi
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Abstract
A norbornane type ester hydrolase that enantio-selectively hydrolyzes a (.+-.) -exo-norbornane type ester represented by Formula I is provided: ##STR1## wherein R is acyl, and A and B are hydrogens, respectively, or where A and B are absent, resulting in a carbon-carbon double bond between the carbons to which A and B are attached in Formula I. The norbornane type ester hydrolase has an optimal pH of approximately 8 and a stable pH range of approximately 6 to 8.
Claims6
An isolated DNA encoding a norbornane type ester hydrolase consisting of an amino acid sequence from Met in the 1 position to Ala in the 388 position of SEQ ID No. 2.
An isolated DNA consisting of a base sequence from A in the 1 position to C in the 1164 position of SEQ ID No. 1.
Dependencies are inferred from the claim text.