Probes and assays for calcium channel .alpha..sub.2 subunit-encoding nucleic acids
AssigneeSibia Neurosciences, Inc.
InventorsSteven Bradley Ellis, Mark E. Williams, Michael Miller Harpold, Arnold Schwartz, Robert Brenner
Life of this patent
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Abstract
Calcium channel (alpha).sub.1 -subunit and (alpha).sub.2 -subunit-encoding DNA, and related compositions and methods, are provided.
Claims18
An isolated single-stranded nucleic acid having a sequence which is:
- (a) a fragment of the sequence shown in SEQ ID NO:
- 2 comprising at least 12 contiguous bases of the sequence from nucleotides 282 to 3627 of SEQ ID NO:
- 2, or
- (b) the complement of the sequence of (a).
An isolated single-stranded nucleic acid having a sequence which is:
- (a) a fragment of the sequence shown in SEQ ID NO:
- 3 comprising at least 12 contiguous bases of SEQ ID NO:
- 3, or
- (b) the complement of the sequence of (a).
An isolated single-stranded nucleic acid comprising a sequence which is:
- (a) a fragment of the sequence shown in SEQ ID NO:
- 2 comprising at least 30 contiguous bases of the sequence from nucleotides 71 to 3802 of SEQ ID NO:
- 2, or
- (b) the complement of the sequence of (a).
An isolated single-stranded nucleic acid comprising a sequence which is:
- (a) a fragment of the sequence shown in SEQ ID NO:
- 3 comprising at least 30 contiguous bases of SEQ ID NO:
- 3, or
- (b) the complement of the sequence of (a).
An isolated nucleic acid molecule comprising at least 30 contiguous base pairs of the sequence set forth in SEQ ID No. 2 between nucleotides 71-3802.
An isolated nucleic acid molecule comprising at least 30 contiguous base pairs of the sequence set forth in SEQ ID No. 3.
Dependencies are inferred from the claim text.