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US 5,686,089 AGranted
Tissue moisturizing and antimicrobial compositions
AssigneeThe Procter & Gamble Company
InventorsSekhar Mitra, George Endel Deckner
Life of this patent
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Abstract
The present invention relates to improved topical pharmaceutical compositions having improved aesthetics which are useful for imparting antimicrobial actives. In particular, it relates to topical moisturizing compositions containing one or more antimicrobial active compounds. These compositions are also useful for providing relief from symptoms associated with, for example, vaginal yeast infections.
Claims15
A pharmaceutical composition for moisturizing membranous tissue and treating infections comprising:
- (a) from about 0.01% to about 4% of clotrimazole;
- (b) from about 1% to about 10% of a moisturizing component selected from the group consisting of C.sub.3 -C.sub.6 diols and triols, urea, guanidine, elycolic acid and glycolate salts, lactic acid and lactate salts, polyhydroxy alcohols, polyethylene glycol, sugar and starches, sugar and starch derivatives, D-panthenol, hyaluronic acid, lactamide, monoethanolamine, acetamide monoethanolamine, and mixtures thereof;
- and
- (c) a pharmaceutically-acceptable aqueous gel carrier consisting essentially of from about 0.05% to about 1% of a water-soluble, nonionic polyacrylamide gelling agent comprising monomers selected from the group consisting of acrylamide and methacrylamides
- wherein said composition has a viscosity of from about 40,000 about 100,000 cps (20.degree. C., heat Brookfield RVT).
2 more elements
Dependencies are inferred from the claim text.