Cyclodextrin inclusion complex of taxol, and method for its production and its use

A method for the improvement of the solubility of taxol comprising:

• adding taxol to an aqueous solution of 2,6-di-O-methyl-.beta.-cyclodextrin at a molar ratio of 1-20, times with respect to said taxol, and
• then stirring or shaking.

A method for producing an inclusion product of taxol included in a cyclodextrin, which method comprises:

• dissolving taxol in a solvent, said solvent being selected from the group consisting of (i) acetonitrile and water in a volume ratio of 1:1, (ii) acetone and water in a volume ratio of 1:1 and (iii) methanol and water in a volume ratio of 1:1, and
• then adding 2,6-di-O-methyl-.beta.-cyclodextrin, while stirring or shaking.

A method for improving the solubility of taxol, which comprises:

• dissolving taxol in a solvent, said solvent being selected from the group consisting of (i) acetonitrile and water in a volume ratio of 1:1, (ii) acetone and water in a volume ratio of 1:1 and (iii) methanol and water in a volume ratio of 1:1, and then adding 2,6-di-O-methyl-.beta.-cyclodextrin, while stirring or shaking.

A 2,6-di-O-methyl-.beta.-cyclodextrin inclusion complex of taxol.