DNA coding for variable region to human influenza A type virus
AssigneeTakara Shuzo Co., Ltd.
InventorsYoshinobu Okuno, Atsushi Oshima, Hirofumi Yoshioka, Takashi Takabatake, Ikunoshin Kato
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Abstract
An isolated DNA is provided coding for the variable region of an anti-human influenza A type virus antibody having the following characteristics: (a) specifically binds to the stem region of haemaggulutinin molecule of H1N1 and H2N2 subtypes of human influenza A type virus but does not specifically bind to the stem region of haemaggulutinin molecule of H3N2 subtype; and (b) has a neutralization activity for the H1N1 and H2N2 subtypes of human influenza A type virus but no neutralization activity for the H3N2 subtype.
Claims5
An isolated DNA coding for the variable region of an anti-human influenza A type virus antibody, said antibody having the following characteristics (a) and (b):
- (a) specifically binds to the stem region of haemaggulutinin molecule of H1N1 and H2N2 subtypes of human influenza A type virus but does not specifically bind to the stem region of haemaggulutinin molecule of H3N2 subtype;
- and
- (b) has a neutralization activity for the H1N1 and H2N2 subtypes of human influenza A type virus but no neutralization activity for the H3N2 subtype.
Dependencies are inferred from the claim text.