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US 5,684,044 AGranted
Methods for improved topical delivery of lactic acid
AssigneeTristrata, Inc.
InventorsRuey J. Yu, Eugene J. Van Scott
Life of this patent
Estimating the term…
Abstract
Methods for improved topical delivery of lactic acid comprising forming a topically acceptable composition by admixing lactic acid and an amphoteric or pseudoamphoteric agent, and applying said topically acceptable composition to the skin.
Claims12
A method for improved topical delivery of lactic acid, said method comprising the steps of:
- A. forming a topically acceptable composition by admixing lactic acid and an amphoteric or pseudoamphoteric agent selected from the group consisting of glycine, alanine, valine, leucine, isoleucine, serine, threonine, cysteine, cystine, methionine, asparagine, glutamine, arginine, lysine, 5-hydroxylysine, histidine, phenylalanine, tyrosine, tryptophan, 3-hydroxyproline, 4-hydroxyproline, proline, homocysteine, homocystine, homoserine, ornithine, citrulline, creatine, aminoaldonic acids, aminouronic acids, aminoaldaric acids, lauryl aminopropylglycine, neuraminic acid, desulfated heparin, deacerylated hyaluronic acid, hyalobiuronic acid, chondrosine deacetylated chondroitin, creatinine, 2-aminobutanoic acid, 4-aminobutanoic acid, 2-amino-2-methylpropanoic acid, 2-methyl-3-aminopropanoic acid, theanine, phenylglycine, canavanine, canaline, 4-hydroxyarginine, 4-hydroxyornithine, 2,4-diaminobutanoic acid, 2,3-diaminopropanoic acid, 2,6-diaminopinelic acid, 2-amino-3-phenylbutanoic acid, taurine, methionine sulfoxide, methionine sulfone, 3,5-diiodotyrosine, thyroxine, monoiodotyrosine, pipecolic acid, 4-aminopipecolic acid, 4-methylproline, glycylglycine, carnosine, anserine, ophidine, homocarnosine, .beta.-alanylarginine, glutathione, ophthalmic acid, norophthalmic acid, cocoamphoglycine, cocoamphopropionate, cocoamphopropylsulfonate, phosphatidyl ethanolamine, phosphatidyl serine, and shingomyelin, and wherein said composition is formulated to have a pH less than or equal to 4.2;
- and
- B. applying said topically acceptable composition to the skin.
Dependencies are inferred from the claim text.