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US 5,684,020 AGranted
Piperazine, piperidine and 1,2,5,6-tetrahydropyridine
AssigneeAdir et Compagnie
InventorsJean-Louis Peglion, Aimee Dessinges, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Alain Gobert
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Abstract
A compound selected from those of formula: ##STR1## wherein: A-B, n, D and E are as defined in the specification, their racemic mixtures, and their optical isomers, and also the physiologically tolerable salts thereof with appropriate acids. The products of the invention may be used therapeutically.
Claims6
A compound selected from those of formula I:
- ##STR45## wherein A-B is selected from the group consisting of:
- CH.sub.2 --CH and CH.dbd.C,
- n is selected from the group consisting of zero and 1 to 6 inclusive,
- D represents one of the following bicyclic systems:
- ##STR46## wherein:
- R.sub.1 and R.sub.2, which are identical or different, are each selected from the group consisting of hydrogen, halogen, straight-chain and branched alkyl and alkoxy each having 1 to 5 carbon atoms inclusive, and hydroxy;
- and
- E represents one of the following heterocycles:
- ##STR47## with the proviso that E does not represent:
- ##STR48## when D is ##STR49## its racemic mixtures or racemates and optical isomers or enantiomers and salts thereof with a pharmaceutically acceptable acid.
7 more elements
Dependencies are inferred from the claim text.