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US 5,684,003 AGranted
5-HT.sub.4 receptor agonists
AssigneeNisshin Flour Milling Co., Ltd.
InventorsHaruhiko Kikuchi, Hiroaki Satoh, Masashi Suzuki, Ruta Fukutomi, Masahiro Ueno, Koichiro Hagihara, Takeo Arai, Setsuko Mino, Yumiko Noguchi
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Abstract
Compounds of formula (I) and pharmaceutically acceptable salts thereof are selective agonists for 5-HT.sub.4 receptors. ##STR1## wherein Ak is a C.sub.3 -C.sub.6 alkyl group, and R is a C.sub.2 -C.sub.6 alkyl group, a C.sub.3 -C.sub.6 alkenyl group, a C.sub.3 -C.sub.6 alkynyl group, a C.sub.3 -C.sub.7 cycloalkyl group or a C.sub.3 -C.sub.6 cycloalkylmethyl group.
Claims11
A compound of formula (I) or a pharmaceutically acceptable salt thereof:
- ##STR50## wherein Ak is a C.sub.3 -C.sub.6 alkyl group, and R is a C.sub.3 -C.sub.6 alkyl group, a C.sub.3 -C.sub.6 alkenyl group, a C.sub.3 -C.sub.6 alkynyl group, a C.sub.3 -C.sub.7 cycloalkyl group or a C.sub.3 -C.sub.6 cycloalkylmethyl group.
Dependencies are inferred from the claim text.