Human phosphorylase kinase gamma subunit
AssigneeIncyte Pharmaceuticals, Inc.
InventorsOlga Bandman, Surya K. Goli
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Abstract
The present invention provides a novel human phosphorylase kinase gamma subunit (HPHKG) and the polynucleotide which identifies and encodes HPHKG. The invention provides for expression vectors and host cells comprising the nucleic acid sequence encoding HPHKG. The invention also provides pharmaceutical compositions containing purified HPHKG or antisense molecules to HPHKG for the treatment of diseases associated with expression of HPHKG. The invention also includes diagnostic compositions containing the polynucleotide, fragments or the complement thereof, which hybridize with the genomic sequence or the transcript of polynucleotides encoding HPHKG or anti-HPHKG antibodies which specifically bind to HPHKG, and the use of such compositions for diagnosis of disease.
Claims6
An isolated and purified human phosphorylase kinase gamma subunit polynucleotide sequence encoding the polypeptide of SEQ ID NO:1.
A polynucleotide sequence which is complementary to the sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.