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US 5,683,894 AGranted
Recombinant nerve growth factor
AssigneeUniversity of California
InventorsRobert H. Edwards, William J. Rutter
Life of this patent
Estimating the term…
Abstract
A method for producing pure, active, mature recombinant Nerve Growth Factor-beta is disclosed, as is the protein so produced.
Claims5
A process for preparing biologically active recombinant NGF-beta, which comprises:
- (a) expressing a gene encoding pro-NGF-beta in a eukaryotic expression host into which DNA comprising said gene and at least one regulatory element has been introduced;
- and
- (b) treating said pro-NFD-beta so produced with a trypsin like protease to yield biologically active recombinant NGF-beta.
Dependencies are inferred from the claim text.