Orally-administered dosage form for animals, preparation method therefor and uses thereof

Dosage form for orally administering chemical or medicinal substances, comprising a solid central core containing one or more bioactive substances and an outer layer or coating, wherein:

• said central core being porous and water-soluble and comprising:
• at least one substance selected from the group consisting of binders selected from the group consisting of polypeptides, high molecular weight polysaccharides, polymers capable of giving colloidal solutions and colloids, and diluents selected from the group consisting of polyols, metal oxides, carbonates, phosphates or micro-crystalline cellulose, the overall quantity of binder and diluent being between 50 and 98% by weight relative to the said central core, and
• an effective quantity of at least one bioactive substance, and
• said outer layer comprising:
• at least one lipid substance selected from the group consisting of fatty alcohols, fatty acids, glycerol esters, hydrogenated oils, waxes, paraffin, lanolin, coconut oil and fatty acid salts;
• an agent for modulating the disintegration and the adhesion of the said outer layer, soluble or dispersible in the lipid mass, selected from the group consisting of polymers selected from the group consisting of acrylic resins, polyvinyl acetates, polyalkylene resins, ethylene/vinyl acetate (EVA) copolymers, cross-linked polymers of starch, dextran, insulin or vinylpyrrolidone and cellulose derivatives selected from the group consisting of hydroxypropyl cellulose, hydroxypropyl methylcellulose, ethyl cellulose, carboxymethylcellulose;
• and
• natural or synthetic palatable substances selected from the group consisting of products of purely plant origin, products of animal origin selected from the group consisting of meats or fish meals, and flavours.