Galenic preparation of therapeutic composition comprising aspirin

Abstract

Mecidinal specialty in galenic presentation and constituted in particular by a pastille, granule, pill, tablet or the like, adapted to be sucked by the user or with sublingual administration. At least one active product in microdispersed form within the substrate. Method of presenting a therapeutical composition for internal use, particularly for administration per os, in galenic presentation, and containing at least one active principle in solid form adsorbed on a substrate. The active product is distributed therein in the state of finely dispersed microparticles. The method is of the type comprising the phases of: dissolution of the starting active principle in an appropriate solvent; impregnation of the solution thus formed on a food support of appropriate structure pharmaceutically compatible with the active principle; and evaporation of the solvent from the solution adsorbed within the support, provoking reconstitution of the active principle by the formation of microcrystals adsorbed on the walls and within the substrate. The solvent is constituted by a binary system comprising a main solvent, of organic nature, and an adjuvant, of solid type at ambient temperature and soluble in the main solvent. The adjuvant in addition has lubricating properties.

Dependencies are inferred from the claim text.