Reactive tricalcium phosphate compositions
AssigneeNorian Corporation
InventorsMark Fulmer, Brent R. Constantz, Ira C. Ison, Bryan M. Barr
Life of this patent
Estimating the term…
Abstract
Methods for producing a room temperature stable, phase pure .alpha.-C.sub.3 P product, and compositions derived therefrom, are provided. In the subject method, a tricalcium phosphate source is heated to a temperature sufficient to convert substantially all of said tricalcium phosphate source to a substantially phase pure .alpha.-C.sub.3 P product. The temperature of the resultant product is rapidly cooled to a temperature below about 700.degree. C., resulting in a room temperature stable, reactive .alpha.-C.sub.3 P product. The resultant .alpha.-C.sub.3 P product may be milled to provide an .alpha.-C.sub.3 P composition which may find use in the preparation of calcium phosphate cements.
Claims10
A method for producing a phase pure reactive .alpha.-C.sub.3 P composition, said method comprising:
- heating a room temperature stable tricalcium phosphate source to a first temperature sufficient to cause a substantially uniform transition to phase pure .alpha.-C.sub.3 P;
- rapidly cooling said phase pure .alpha.-C.sub.3 P to a second temperature below about 700.degree. C. in less than about 10 min resulting in a room temperature stable, substantially phase pure .alpha.-C.sub.3 P product;
- and
- milling said room temperature stable, substantially phase pure .alpha.-C.sub.3 P product for a period of time ranging from 10 min to 2 hr to produce a composition having a surface area ranging from 2.5 to 3.5 m.sup.2 /g and having a particle size distribution which is graphically represented as a curve having a broad peak and a leading shoulder;
- whereby said phase pure reactive .alpha.-C.sub.3 P composition is produced.
A method for producing a phase pure reactive .alpha.-C.sub.3 P composition comprising:
- heating a room temperature stable tricalcium phosphate source to a first temperature sufficient to cause a substantially uniform transition to phase pure .alpha.-C.sub.3 P;
- rapidly cooling said phase pure .alpha.-C.sub.3 P to a second temperature below 700.degree. C. in less than 10 min resulting in a room temperature stable, substantially phase pure .alpha.-C.sub.3 P;
- and
- attritor milling said room temperature stable, substantially phase pure .alpha.-C.sub.3 P for a period of time ranging from 0.5 to 2.0 hr to produce a composition having a surface area ranging from 2.5 to 3.5 m.sup.2 /g and having a particle size distribution which is graphically represented as a curve having a broad peak and a leading shoulder.
A reactive phase pure .alpha.-C.sub.3 P composition comprising particles of room temperature stable, substantially phase pure .alpha.-C.sub.3 P ranging in size from 3 to 5 .mu.m, wherein said composition has a surface area ranging from 2.5 to 3.5 m.sup.2 /gm and a particle size distribution which is graphically represented as a curve having a broad peak and a leading shoulder, wherein said leading shoulder is displaced from said broad peak by between about 2 and 4 .mu.m and said broad peak occurs at about 5 .mu.m.
A reactive phase pure .alpha.-C.sub.3 P composition comprising:
- particles of room temperature stable, substantially phase pure .alpha.-C.sub.3 P, wherein the mean particle size of said particles is about 4 .mu.m, and said composition has a surface area of about 3 m.sup.2 /gm and a particle size distribution as represented in FIG. 4a.
Dependencies are inferred from the claim text.