Treatment of ovarian estrogen dependent conditions
AssigneeThe Medical College of Hampton Roads
InventorsGary D. Hodgen, Robert F. Williams, Daniel Grow
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Abstract
A method of treating an ovarian estrogen dependent condition such as endometriosis, uterine leiomyomata, PMS or DUB involving the administration of gonadotropin releasing hormone analog and the administration of antiprogestin, which will provide a therapeutic method for long term treatment without rapid loss of bone density, as occurs using GnRH analogs alone.
Claims16
A method of treating an ovarian estrogen dependent condition which comprises administering gonadotropin releasing hormone analog to a women for a period of time of at least about 30 days which is sufficient to lower the circulating estrogen level in the blood to about 20 pg/ml or less and after said about thirty days administering an anti-proliferative and bone conserving amount of antiprogestin, wherein said analog is a gonatropin releasing hormone agonist or antagonist.
Dependencies are inferred from the claim text.