Device for delivery of substances and methods of use thereof
AssigneeCambridge NeuroScience, Inc.
InventorsStanley M. Goldin, Nagesh K. Mahanthappa, Judith Sudhalter, Eric Fine
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Abstract
This invention comprises devices and methods for producing a composite microporous membrane specifically tailored to be useful for optimizing the delivery of macromolecules to a therapeutic target.
Claims20
A device comprising a microporous underlayment with microcapillary pores wherein said pores are coated but not completely filled by a microskin to which a biologically active macromolecular agent is bound.
A device comprising a microporous underlayment with microcapillary pores wherein said pores are coated but not completely filled by a microskin to which a biologically active macromolecular agent is bound and is releasable therefrom.
A device comprising a microporous underlayment with microcapillary pores comprised of cellulose, wherein said pores are coated but not completely filled by a microskin comprised of collagen to which glial growth factor 2 is bound and is releasable therefrom.
Dependencies are inferred from the claim text.