Bone regeneration membrane
AssigneeLaboratorium fur experimentalle Chirurgie, Forschungsinstitut
InventorsSylwester Gogolewski, Richard P. Meinig, Stephan M. Perren
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Abstract
A bone regeneration membrane containing resorbable or degradable, polymeric and/or polymeric-ceramic material with a glass transition temperature in the range of -30.degree. to +200.degree. C. The novel membrane can be used for the spontaneous regeneration of bone and for the improved application of autologous or allogenic graft materials and therapeutic agents.
Claims30
A thin, resorbable bone regeneration membrane containing interconnected micropores and having a thickness between 0.05 mm and 5.0 mm, said membrane comprising resorbable or degradable polymeric material wherein the glass transition temperature of said polymeric material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0.
A membrane according to claim 16, which has a shape memory.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, and further comprising reinforcement including resorbable and/or degradable fibers.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, wherein said membrane further contains antiosteomyelitis agents.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, wherein said membrane further contains antineoplastic agents.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, wherein said membrane further contains osteoconductive agents of autogenic, allogenic, xenogenic, or synthetic origin.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, wherein said membrane further contains osteoinductive agents of autogenic, allogenic, xenogenic, or synthetic origin.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, wherein said membrane is formed in a tubular form with a longitudinal slit adapted to form semi-occlusive fits at the two extremities of the tube formed by said membrane for fixation to bones.
A bone regeneration membrane comprising resorbable or degradable polymeric and/or polymeric-ceramic material wherein the glass transition temperature of said polymeric and/or polymeric-ceramic material is in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0, said membrane having interconnected micropores therein, wherein said membrane is formed in a tubular form with a longitudinal slit having ends shaped to form semi-occlusive fits over cortical bone ends and within medullary canals of long or tubular bones.
A thin, resorbable bone regeneration membrane containing interconnected micropores and having a thickness between 0.05 mm and 5.0 mm, said membrane consisting of resorbable or degradable polymeric material having a glass transition temperature in the range of body temperature to 200.degree. C. and the molecular weight distribution of said polymeric material is in the range of 1.2 to 100.0.
Dependencies are inferred from the claim text.