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US 5,675,007 AGranted
Derivatives of quinuclidine n-oxide as muscarinic receptor ligands
AssigneeSmithKline Beecham Corporation
InventorsJohn Keogh, Gary Thomas Borrett, Steven Mark Bromidge, Erol Ali Faruk, Mark Jason Hughes, John Kitteringham, Martyn Voyle
Life of this patent
Estimating the term…
Abstract
A compound of formula (I) or a pharmaceutically acceptable salt thereof (I) wherein R.sub.1 represents (a), R.sub.2 is a group OCH.sub.3, and R.sub.3 is cyano, for use in the treatment and/or prophylaxis of dementia in mammals.
Claims11
A compound of formula (I) or a pharmaceutically acceptable salt thereof:
- ##STR12## wherein R.sub.1 represents ##STR13## R.sub.2 is a group OCH.sub.3, and R.sub.3 is cyano.
R-(Z)!-.alpha.-(methoxyimino)-.alpha.-(1-azabicy clo2.2.2!oct-3-yl)acetonitrile-1-oxide or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.